| Navy | The Royal Navy |
| Type | Submarine |
| Class | R |
| Pennant | N 88 |
| Built by | Vickers Armstrong (Barrow-in-Furness, U.K.) |
| Ordered | 28 Feb 1929 |
| Laid down | 17 Jul 1929 |
| Launched | 11 Jun 1930 |
| Commissioned | 7 Dec 1930 |
| Lost | 6 Dec 1940 |
| History | HMS Regulus (Lt.Cdr. Frederick Basil Currie, RN) left Alexandria to patrol in southern Adriatic on 23 November 1940. She is most likely mined on 6 December 1940 off Taranto, Italy. |
Commands listed for HMS Regulus (i) (N 88)
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| Commander | From | To | |
| 1 | Cdr. John Marston Money, RN | 15 Jan 1939 | 31 Jul 1940 |
| 2 | Lt.Cdr. Frederick Basil Currie, RN | 31 Jul 1940 | 6 Dec 1940 |
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